More Prescriptions, Higher Risk
The researchers noted a clear pattern: the more you take, the higher the risk.
- 12+ prescriptions: 40% higher chance of dementia
- 12+ prescriptions: 65% higher chance of MCI
These findings held even after accounting for age, other health conditions, and medications.
Why the Green Ring Isn’t the Whole Story
Gabapentin has been around since the 1990s, originally approved for epilepsy. Over the years, it became a go-to for nerve pain, chronic back pain, post-shingles pain, and restless leg syndrome, often seen as a safer alternative to opioids.
Many gabapentin users also have limited mobility — another factor linked to dementia. However, this study matched patients for mobility, suggesting the drug itself may contribute to cognitive changes.
What Patients Should Do
This isn’t a call to panic — but it does highlight the importance of awareness. Experts recommend:
- Regular cognitive check-ins with your doctor
- Discussing alternatives or adjusting dosage if possible
- Avoiding long-term use unless absolutely necessary
Gabapentin remains safer than many other pain medications, but informed choices are essential. As the study concludes: “Our findings indicate an association between gabapentin prescription and dementia or cognitive impairment within 10 years.”